In the new network-centric healthcare IT environment, standardization of information representation, organization and dissemination is the first step towards achieving semantic interoperability among heterogeneous systems. In this paper, we discuss roadblocks encountered in a real-world project to integrate two disparate healthcare systems based on HL7 v3 standards. (2019). ACTA SCIENTIAE, 2(1). https://periodicosulbra.org/index.php/acta/article/view/97